Tag: Alkylating agent

Temozolomide, an oral chemotherapy agent, can cross the crucial blood-brain barrier, making it effective for treating certain brain cancers. So, **what does temozolomide do** to target and destroy these challenging tumors?

An estimated 500,000 patients worldwide are treated with cyclophosphamide annually [1.7.1]. But **what kind of medication is cyc?** It is a potent chemotherapy and immunosuppressant drug used to treat various cancers and autoimmune disorders [1.2.1, 1.4.3].

First approved in the United States in 1969, the chemotherapy agent procarbazine has been a mainstay in treating certain types of cancer, especially when used in combination with other drugs,. The most commonly recognized brand name answering the question "What is another name for procarbazine?" is Matulane, although other versions exist globally. This drug belongs to a class of medications called alkylating agents, which work by targeting and damaging the DNA of cancer cells.

In a long-term study of patients with low-grade glioma, the addition of procarbazine-based chemotherapy to radiation therapy extended median overall survival from 7.8 years to 13.3 years [1.2.2]. This highlights the critical question: exactly how effective is procarbazine in modern oncology?

According to its FDA approval, Bendeka is indicated for the treatment of two types of blood cancer: chronic lymphocytic leukemia (CLL) and a specific type of non-Hodgkin lymphoma (NHL). As an intravenous chemotherapy agent, Bendeka's purpose is to interfere with and kill cancer cells.

Uniplatin is a brand name for cisplatin, a widely used chemotherapy agent. This medicine belongs to the class of alkylating agents and is used to treat various types of advanced or metastatic cancers, including ovarian and testicular cancer. Its purpose is to interfere with the DNA of rapidly dividing cancer cells, ultimately causing their death.

Cyclophosphamide (CYC), a potent medication used since 1959, is a cornerstone in treating various cancers and autoimmune diseases [1.8.3]. So, **what is a CYC drug?** It's a powerful chemotherapy and immunosuppressive agent belonging to a class called alkylating agents [1.2.1, 1.2.2].

Dacarbazine, commonly known as **DTIC**, is a type of alkylating chemotherapy agent primarily used to treat certain cancers. It works by damaging the DNA of cancer cells, which prevents them from dividing and growing.

Approved for use in the United States in 1969, procarbazine remains a key chemotherapy drug used in combination regimens to treat advanced Hodgkin's lymphoma and certain brain cancers [1.7.3]. So, what does procarbazine do? It functions as an alkylating agent, slowing or stopping the growth of cancer cells [1.3.1].

In a retrospective study of 85 newly diagnosed glioblastoma multiforme (GBM) patients, the cohort receiving carmustine wafers had a 2-year survival rate of 47%, compared to 29% for the non-carmustine cohort [1.14.1]. So, **what does carmustine do** to achieve these results? It is a powerful chemotherapy drug used to treat several types of cancer.