Tag: Allodynia

While not a confirmed side effect listed in clinical trials, emerging patient reports and medical professional observations raise the question: **Does mounjaro cause allodynia?** These anecdotal accounts, along with case studies involving other GLP-1 agonists like semaglutide, are prompting a closer examination of this potential adverse reaction.

According to placebo-controlled clinical trials, 3.2% of Mounjaro patients reported injection site reactions, which can include localized pain. So, is painful skin a side effect of Mounjaro? Mild pain or tenderness at the injection site is a relatively common and manageable occurrence, but it can also indicate other types of skin reactions.

In clinical trials for Wegovy, about 2% of adult patients reported dysesthesia, a category of nerve sensations that includes allodynia [1.2.3, 1.2.4]. This article explores the question: Does Wegovy cause allodynia, a condition where non-painful stimuli cause pain?

In 2019, approximately 50.2 million U.S. adults experienced chronic pain, with over 22% using prescription opioids [1.6.2]. A perplexing issue in jejich management is the opioid paradox, a state where these potent painkillers actually increase pain sensitivity [1.2.2].

In a recent report published in the *American Journal of Health-System Pharmacy*, four patients taking the GLP-1 drug semaglutide experienced allodynia, a painful skin sensitivity, after increasing their dose. While the exact link is still being investigated, this raises important questions about whether **does Ozempic cause allodynia?**