Tag: Alpha 2 delta subunit

In 2021, approximately 70.9 million prescriptions for gabapentin were dispensed in the United States, making it one of the country's most prescribed medications. But what does gabapentin do to neurotransmitters to achieve its therapeutic effects?

Despite its structural resemblance to the neurotransmitter GABA, gabapentin's mechanism of action is distinctly different and more complex, primarily revolving around its unique interaction with voltage-gated calcium channels to modulate nerve activity. This unique action is what makes gabapentin work effectively for certain types of pain and epilepsy.