Tag: Alpha adrenergic blockade

The tricyclic antidepressant amitriptyline has long been associated with cardiovascular side effects, including a drop in blood pressure. This is because it **does amitriptyline relax blood vessels**, but the full picture is more complex and dose-dependent, with potential for opposing effects at different concentrations.

While many antipsychotics are associated with pupil dilation (mydriasis) due to anticholinergic effects, certain older and atypical antipsychotic medications have been linked to miosis, or constricted pupils. This less common phenomenon often occurs in the context of overdose or is driven by specific receptor interactions.