Tag: Amiodarone toxicity

Over 90% of patients on long-term amiodarone therapy develop corneal microdeposits, indicating the drug's widespread distribution. Beyond this common ocular finding, the serious question of what organ does amiodarone damage extends to the lungs, liver, and thyroid, presenting significant clinical challenges.

Due to its extremely long and variable half-life—averaging around 58 days—the antiarrhythmic drug amiodarone cannot be immediately reversed. Instead of an antidote, managing amiodarone's effects or toxicity involves discontinuing the medication and implementing supportive care, a process that can take weeks or months to see full effect.

While many life-saving medications exist, drug-induced interstitial lung disease (DIILD) is a recognized but potentially overlooked side effect, accounting for 3% to 5% of all ILD cases. Understanding **which drugs cause ILD** is a critical first step for patients and clinicians to ensure early detection and management of this serious condition.