Understanding What Drug Causes Loss of Motivation (Drug-Induced Apathy)
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5 min read
Studies suggest that between 20% and 92% of patients taking selective serotonin reuptake inhibitors (SSRIs) may experience a clinical apathy syndrome, a key indicator of **what drug causes loss of motivation**. This effect, often termed emotional blunting or amotivational syndrome, is a recognized side effect across various medication classes, not just antidepressants. It is caused by a disruption in the brain's neurochemical reward system, impacting an individual's drive and interest in once-pleasurable activities.