Tag: Amygdala

According to the National Institute on Drug Abuse, stimulants increase dopamine and norepinephrine levels in the brain, fundamentally changing how the brain's reward and emotional centers operate. This article explores the precise neuropharmacological mechanisms behind the question: how do stimulants affect the limbic system?

The amygdala, a key brain region for emotion, is often overactive in anxiety disorders, triggering exaggerated fear and distress. A number of pharmacological treatments exist, and understanding what medication calms the amygdala is essential for individuals seeking to manage these conditions.

According to a University of Oxford study, THC was directly linked to an increase in paranoia in 1 in 5 participants [1.7.2]. Understanding **what strain makes you paranoid** involves looking at THC content, CBD ratios, and individual brain chemistry to avoid unwanted anxiety [1.7.2].

Functional magnetic resonance imaging (fMRI) studies have shown that in people with depression and anxiety, the brain's amygdala often displays heightened activity in response to negative stimuli. Addressing this overactivity is one of the key therapeutic goals of sertraline (commonly known as Zoloft), which works to modulate emotional processing pathways.

Research suggests that over-activation of the amygdala, the brain's fear hub, can contribute to anxiety disorders. Determining **what drug calms the amygdala** involves understanding how different classes of medications modulate key neurotransmitter systems to reduce fear and anxiety responses.