Skip to content

Tag: Anesthetic dosing

Explore our medication guides and pharmacology articles within this category.

What is the 10/8-6 rule for propofol? An Overview of a Manual Infusion Regimen

4 min read
First developed in the 1990s through computer simulations, the **what is the 10/8-6 rule for propofol?** describes a simplified manual infusion scheme for continuous propofol administration. This step-down dosing approach was designed to help clinicians maintain a stable, targeted blood concentration of the anesthetic drug during total intravenous anesthesia (TIVA).