Can I take Benadryl with anti-anxiety meds?
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4 min read
According to addiction and mental health experts, combining Benadryl (diphenhydramine) with anti-anxiety medications, particularly benzodiazepines like Xanax, is extremely dangerous due to intensified central nervous system (CNS) depression. This combination can lead to severe side effects and even overdose, highlighting why you should always ask, 'Can I take Benadryl with anti-anxiety meds?' before combining these drugs.