Which Mechanism of Action is True of Aspirin? A Deep Dive into its Pharmacology
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4 min read
The British pharmacologist Sir John Vane's discovery in 1971 revealed that aspirin primarily works by inhibiting the cyclooxygenase (COX) enzyme, a breakthrough that earned him a Nobel Prize. This irreversible inhibition is the foundational answer to the question: **Which mechanism of action is true of aspirin?** and explains its wide-ranging therapeutic effects.