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Tag: Anticholinergic side effects

Explore our medication guides and pharmacology articles within this category.

What is a safer alternative to oxybutynin?

3 min read
Over 33 million U.S. adults live with overactive bladder (OAB) symptoms, and for many, oxybutynin is a common prescription. However, because of its significant anticholinergic side effects, many individuals seek to understand what is a safer alternative to oxybutynin.

How much amitriptyline should I take for interstitial cystitis?: Understanding Dosage and Treatment

3 min read
Up to 64% of interstitial cystitis (IC) patients have reported improvement with long-term amitriptyline treatment, highlighting its potential efficacy. When determining **how much amitriptyline should I take for interstitial cystitis**, dosage is carefully managed, typically starting low and gradually adjusted upward to balance symptom relief with tolerability of side effects.

Is mirtazapine anticholinergic? Understanding the Pharmacology

4 min read
Mirtazapine is an atypical tetracyclic antidepressant that is often used to treat major depressive disorder. Unlike older tricyclic antidepressants (TCAs), mirtazapine has a different pharmacological profile that involves weak muscarinic antagonism, meaning it has minimal anticholinergic activity and a lower risk of associated side effects.

Can atropine cause constipation?

4 min read
As an anticholinergic medication, atropine is well-known to inhibit the parasympathetic nervous system. This action can significantly reduce gastrointestinal motility, and, as a result, a common side effect is constipation.

Does ZzzQuil Affect the Kidneys? Understanding the Risks

4 min read
Case studies have shown that the active ingredient in ZzzQuil, diphenhydramine, can have adverse effects on kidney function in certain individuals. While typically safe for short-term use in healthy adults, special precautions are necessary for specific populations, and it is crucial to understand **does ZzzQuil affect the kidneys** under different circumstances.

Understanding the Bladder Effects: Can Amitriptyline Affect the Bladder?

3 min read
According to the National Institutes of Health, anticholinergic side effects like urinary retention are a known adverse reaction to amitriptyline. This article explores the complex ways **can amitriptyline affect the bladder**, examining both its therapeutic benefits and potential side effects on urinary function.

What is the most common side effect of amitriptyline? A Pharmacological Review

5 min read
While several side effects are commonly reported with amitriptyline, drowsiness and dry mouth consistently rank among the most frequently experienced, largely due to the drug's anticholinergic and antihistamine properties. This article will delve into what is the most common side effect of amitriptyline and provide insight into its causes and management.

Why was orphenadrine discontinued? Unpacking the nitrosamine recall and safety concerns

3 min read
In March 2022, manufacturer Sandoz, Inc. issued a nationwide recall of 13 lots of orphenadrine citrate 100 mg extended-release tablets because of a potentially cancer-causing nitrosamine impurity. However, the story of why was orphenadrine discontinued is more complex, involving long-standing safety concerns and poor risk-benefit ratios that ultimately led to its removal from many markets.