Tag: Antidepressant alternatives

According to a 2018 systematic review, amitriptyline demonstrated higher dropout rates due to adverse effects compared to other antidepressants, highlighting why doctors don't like to prescribe amitriptyline as a first-line option. Once a mainstay for depression, this tricyclic antidepressant (TCA) has been largely replaced by newer, safer medications for many conditions.

Up to two-thirds of patients with major depression fail to respond adequately to their first antidepressant medication, leading many to explore what can I replace Prozac with?. Understanding the range of available options, from alternative medications to non-pharmacological approaches, is a crucial step in finding the right treatment path.