Skip to content

Tag: Antidepressant resistance

Explore our medication guides and pharmacology articles within this category.

Can You Become Resistant to Fluoxetine? What to Know About SSRI Tolerance

5 min read
Research suggests that up to 25% of individuals treated for depression with SSRIs, including fluoxetine, may experience a decrease in effectiveness over time, a phenomenon known as tachyphylaxis. This raises the important question: Can you become resistant to fluoxetine, and what can be done if your medication seems to stop working?.