Does Wellbutrin stop working over time? Understanding 'Antidepressant Poop-Out'
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4 min read
According to Johns Hopkins Medicine, breakthrough depression, where a previously effective antidepressant becomes ineffective, affects up to 33% of people using these medications. For those taking bupropion, or Wellbutrin, it is possible for the medication's effects to wane over time, though it is often less prone to this phenomenon than some other antidepressants.
