Understanding What is the Mode of Action of Sulfonamides and Trimethoprim?
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4 min read
The combination of trimethoprim and sulfamethoxazole, a common example of this antibiotic class, was first introduced clinically in the 1970s and quickly gained prominence for its synergistic effect in treating numerous infections. Understanding what is the mode of action of sulfonamides and trimethoprim reveals how these drugs work together to inhibit bacterial growth by disrupting a critical metabolic pathway.