Tag: Antineoplastic

Despite its use on skin conditions, Efudix cream is a topical chemotherapy agent, not an antibiotic. It contains the active ingredient fluorouracil (5-FU), which treats certain precancerous growths and skin cancers by targeting rapidly dividing cells, a fundamentally different mechanism from drugs that fight bacteria.

In clinical trials for advanced-stage cutaneous T-cell lymphoma (CTCL), bexarotene demonstrated an overall response rate of 45-55% in patients refractory to previous systemic therapies. Understanding **what is the mechanism of action of bexarotene** involves exploring its role as a selective retinoid X receptor (RXR) agonist and its profound influence on gene transcription.

Over a dozen clinically approved medications incorporate the carbazole core, a privileged chemical scaffold known for its diverse biological activities. Understanding **what drugs contain carbazole** is key to appreciating its significant role in modern pharmacology and its application across a wide range of therapeutic areas.

Ifosfamide exhibits dose-dependent pharmacokinetics, with varying half-lives depending on the administered amount. What are the doses of ifosfamide depends heavily on the type of cancer being treated, the patient's individual factors, and whether it is used as a standard or high-dose regimen.

Approximately 70-90% of the chemotherapy drug pemetrexed is eliminated through renal excretion. The term **PEM drug** can be ambiguous, but in an oncology context, it almost always refers to pemetrexed, a potent chemotherapy agent used to treat specific types of lung cancer and mesothelioma. Beyond oncology, the acronym PEM represents other drugs and concepts, requiring careful interpretation based on context.

Uniplatin is a brand name for cisplatin, a widely used chemotherapy agent. This medicine belongs to the class of alkylating agents and is used to treat various types of advanced or metastatic cancers, including ovarian and testicular cancer. Its purpose is to interfere with the DNA of rapidly dividing cancer cells, ultimately causing their death.

Arsenic trioxide, an inorganic compound with a long history in medicine, was approved by the FDA in 2000 under the brand name Trisenox® for the treatment of acute promyelocytic leukemia (APL). This once highly fatal blood cancer can now be managed with an ato injection, particularly when used in combination with other therapies.

First approved by the FDA in 1999 for the treatment of cutaneous T-cell lymphoma (CTCL), the medication known as **bexarotene** is a member of the retinoid drug family. However, it is a distinct subclass of retinoids, often called rexinoids, because it selectively targets retinoid X receptors (RXRs) rather than retinoic acid receptors (RARs).

According to the National Cancer Institute, fulvestrant is an antiestrogen medication used to treat certain types of breast cancer. The most common and widely known brand name and another name for fulvestrant is **Faslodex**.

Xeloda, a brand name for the chemotherapy drug capecitabine, is a crucial oral medication utilized in the treatment of several types of cancer. Unlike many other chemotherapy drugs administered intravenously, Xeloda is a pill, making it a more convenient option for many patients. The primary question, "what is xeloda used for?", centers on its effectiveness against fast-growing cancer cells in breast, colon, and other gastrointestinal cancers.