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Tag: Antiplatelet therapy

Explore our medication guides and pharmacology articles within this category.

What are the indications for use of aspirin in an emergency?

3 min read
According to the American Heart Association, a rapid response with aspirin during a suspected heart attack can be life-saving by inhibiting clot formation. Early administration is a cornerstone of emergency cardiac care, significantly reducing mortality in patients with acute coronary syndrome (ACS). This article addresses the critical question: what are the indications for use of aspirin in an emergency?

When to Restart Clopidogrel Post-Op: Navigating the Balance of Risk

4 min read
For patients on antiplatelet medication, premature discontinuation of clopidogrel has been associated with a five- to tenfold increase in the risk of cardiovascular events and death in those with recent stent placement. Determining exactly when to restart clopidogrel post-op requires carefully weighing the risk of surgical bleeding against the risk of potentially life-threatening thrombotic events. This decision is never a one-size-fits-all approach and depends on numerous factors unique to each patient and procedure.

Understanding When to Restart Antiplatelet Therapy After GI Bleed?

4 min read
Following a gastrointestinal (GI) bleed, permanently discontinuing antiplatelet therapy is associated with a significantly increased risk of cardiovascular and cerebrovascular events. The clinical dilemma of deciding **when to restart antiplatelet therapy after GI bleed** requires a careful, individualized balance of weighing re-bleeding risk against potentially fatal thrombotic events.

Understanding What is the Antidote for Plavix?

4 min read
While specific antidotes exist for some blood thinners, there is no direct antidote for Plavix (clopidogrel) because of its irreversible mechanism of action. Its antiplatelet effect lasts for the entire lifespan of the affected platelets, which is about 7 to 10 days.

Which has higher bleeding risk, aspirin or clopidogrel? A detailed comparison.

4 min read
Over 1.5 million people in the U.S. alone are hospitalized each year for gastrointestinal bleeding, a serious risk associated with antiplatelet medications. Assessing which has higher bleeding risk, aspirin or clopidogrel, involves understanding their distinct mechanisms and considering various patient-specific factors beyond a simple drug-to-drug comparison. The answer is nuanced and depends heavily on the type and location of the bleeding event.

Understanding Dual Antiplatelet Therapy: Why are Aspirin and Plavix Given Together?

4 min read
Affecting over 79 million Americans, cardiovascular disease remains the leading cause of death in the United States. To combat life-threatening blood clots, healthcare providers often prescribe a powerful combination known as dual antiplatelet therapy, a key example being the combined use of aspirin and Plavix. This potent pairing provides more complete protection against clot formation than either medication alone.

How to Stop Internal Bleeding from Aspirin: A Medical Emergency Guide

4 min read
Daily low-dose aspirin use in healthy elderly individuals can increase the risk of serious gastrointestinal (GI) bleeding by 60% [1.2.2]. Knowing **how to stop internal bleeding from aspirin** involves recognizing it as a medical emergency that requires immediate professional care, not home treatment.

Do you give aspirin after hemorrhagic stroke?: Weighing the Risks and Benefits

5 min read
Immediately giving aspirin after a stroke can have fatal consequences if the stroke is hemorrhagic rather than ischemic. Medical professionals must first use diagnostic imaging to determine the correct stroke type before any antiplatelet medication, including aspirin, is administered. This critical distinction is based on the opposing pharmacological goals for treating these two conditions.