Tag: Antithymocyte globulin

Used for decades in transplantation, Antithymocyte Globulin (ATG) is a powerful polyclonal antibody with a complex mode of action. Understanding precisely **what is the mechanism of action of ATG?** is crucial for its clinical application in preventing organ rejection and treating conditions like severe aplastic anemia.

Approximately 10-20% of kidney transplant recipients experience acute rejection in the first year. Knowing which of the following is used as first line treatment for a severe cellular rejection episode is critical for managing this immune response and protecting the transplanted organ.