Tag: Apomorphine

Over 75% of people with Parkinson's will experience nausea at some point, often as a side effect of their dopaminergic medications. While many common anti-nausea drugs can be dangerous, it raises a critical question: is ondansetron safe in Parkinson's?.

According to the FDA, the anti-nausea drug Zofran (ondansetron) carries a black box warning about the risk of cardiac arrhythmias and is strictly contraindicated with certain medications. Understanding what is Zofran not compatible with is critical for patient safety and preventing severe complications such as dangerous heart rhythm abnormalities or serotonin syndrome.

According to the FDA, administering intravenous ondansetron can potentially lead to fatal arrhythmias in certain patients, especially when mixed with other QT-prolonging drugs. This highlights why it is crucial to understand **what should you not mix with ondansetron** to prevent serious health complications and ensure safe medication use.

While the lotus has been revered in traditional medicine for millennia, specific compounds rather than the plant itself are under modern pharmacological investigation to determine **what drug is made from lotus**. The primary psychoactive compounds, nuciferine and apomorphine, hold significant interest for potential development into pharmaceutical drugs.

Decades ago, having a bottle of syrup of ipecac in your home medicine cabinet for accidental poisoning was standard advice, recommended by medical authorities like the American Academy of Pediatrics. In response to the question, 'What is an example of an emetic?', syrup of ipecac is the classic answer, but its use has been largely abandoned in favor of safer, more effective treatments due to evidence that it is often ineffective and carries significant risks.

Historically, syrup of ipecac was a common household remedy for poisoning, but its use is now strongly discouraged by medical professionals [1.2.2]. This article explores what are the most common emetics, their mechanisms, and the evolution of poison treatment.

According to the Parkinson's Foundation, around 60% of people with Parkinson's disease (PD) experience "off" episodes, which apomorphine is used for as a rapid and effective treatment. This powerful dopamine agonist helps manage motor fluctuations by acting quickly to restore mobility and control symptoms like stiffness and tremor.

The blue lotus flower, *Nymphaea caerulea*, has been associated with ancient rituals for millennia and is the primary species reputedly linked to producing mild euphoric effects. Many misconceptions exist regarding which lotus varieties possess psychoactive properties, with the true lotus (*Nelumbo nucifera*) being distinct from the water lilies that are said to contain these compounds.

Depictions of the blue lotus (*Nymphaea caerulea*) were found in King Tutankhamun's tomb, hinting at its deep cultural significance and historical use in ancient Egypt. This discovery, along with its reported mind-altering effects, prompts the question: **Are water lilies psychedelic?** The answer is complex and depends heavily on the specific species, its preparation, and dosage.

Historically revered in ancient Egypt for its calming properties, blue lotus has garnered modern interest, but many ask, is blue lotus an opioid? Scientific analysis reveals that while it has psychoactive effects, its active alkaloids, apomorphine and nuciferine, act on dopamine and serotonin systems, not opioid receptors.