Tag: Arachidonic acid

Overproduction of inflammatory mediators from the 5-lipoxygenase (5-LOX) pathway is a major cause of conditions like asthma and allergic rhinitis. The question of **what is lox in inflammation** is complex, as 'LOX' is an acronym for several different enzyme and receptor families that play varied roles in inflammatory processes.

Leukotrienes are potent pro-inflammatory lipid mediators, and their overproduction is linked to significant pathological features of asthma and allergies. But **what is the function of the leukotrienes** in both normal physiological processes and in disease states?