Tag: Auditory system

Yes, a notable and well-documented side effect of high-dose aspirin is ototoxicity, which can cause ringing in the ears. This occurs when the active component, salicylate, reaches toxic levels in the body, leading to a condition known as salicylism.

According to scientific research, a high-dose intake of salicylates, particularly from aspirin, can temporarily induce moderate hearing loss and the sensation of tinnitus. This ototoxic effect is typically dependent on the plasma concentration of the drug, meaning that the risk of auditory issues increases significantly with higher doses. The good news is that for most cases involving acute, high-dose use, the hearing-related symptoms are reversible upon cessation or dose reduction.