Tag: Avascular necrosis

According to research, high-dose or long-term prednisone use is a known risk factor for avascular necrosis, a condition where bone tissue dies from lack of blood supply, and this can cause shoulder pain. It is essential to be aware of the potential musculoskeletal complications associated with this powerful corticosteroid medication.

Systemic corticosteroid use is implicated in nearly one-third of all avascular necrosis (AVN) cases, making it the leading cause of non-traumatic osteonecrosis [1.3.3, 1.3.5]. Understanding **what medicines can cause AVN** is the first step in risk management and prevention.

According to a study involving patients taking high-dose steroids, those concurrently on statin therapy had a significantly lower incidence of avascular necrosis (AVN) than typically expected. This counters the idea that can statins cause avascular necrosis and highlights a protective, rather than causative, role of these cholesterol-lowering drugs in some high-risk scenarios.

According to one study, up to 90% of patients who use glucocorticoids for more than 60 days can develop serious adverse effects. This article explores the irreversible side effects of steroids, detailing the permanent damage that can occur with long-term use.

According to the Mayo Clinic, abrupt cessation of prednisone can cause withdrawal symptoms, including severe fatigue, muscle aches, and joint pain. This experience often leaves patients wondering **why do my joints hurt after taking prednisone?** when the medication was intended to provide relief from inflammation.

According to estimates, corticosteroid-induced osteonecrosis alone accounts for over 10% of the half-million total joint replacements performed annually in the U.S. Determining what medication most commonly causes osteonecrosis is complex, as it depends on the specific drug class and the affected part of the skeleton, with bisphosphonates and corticosteroids being the two primary culprits.