Can Baclofen Cause Dystonia? Understanding a Rare Adverse Effect and Withdrawal Risk
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4 min read
While baclofen is commonly used to treat muscle spasticity, case reports document a paradoxical, albeit rare, side effect: drug-induced dystonia. The relationship between this muscle relaxant and the complex movement disorder of dystonia is nuanced, as baclofen is also used as a treatment for it. Understanding the distinct mechanisms—direct induction and withdrawal-related complications—is critical for patient safety.