Tag: Bacterial ribosome

Aminoglycoside-induced hearing loss has a widely varying incidence, with some studies reporting rates between 2% and 25% [1.8.4]. Understanding how these drugs work is key to their safe use. So, what is the binding site of gentamicin and how does it exert its powerful effects?

Erocin is a brand name for the macrolide antibiotic erythromycin, which belongs to a class of drugs known for stopping the growth of bacteria. By targeting a critical process within bacterial cells, the drug effectively halts the spread of infection.

The bacterial ribosome, responsible for protein synthesis, differs structurally from human ribosomes, making it a highly effective target for antimicrobial drugs. This key difference is exploited by a class of medications to determine **which antibiotics block bacterial protein production**, effectively neutralizing harmful bacteria.

Discovered in 1943 from the bacterium *Streptomyces griseus*, streptomycin was the first antibiotic effective against tuberculosis [1.7.1, 1.7.3]. This article explains the detailed pharmacology of **how does streptomycin work** to inhibit bacterial protein synthesis and treat infections.