Tag: Bacteroides

Cefepime, a potent fourth-generation cephalosporin, is a key antibiotic in treating serious aerobic infections, yet its activity against anaerobes like *Bacteroides* is notoriously poor. This limited spectrum necessitates the addition of an anaerobic agent, most commonly metronidazole, when treating infections with a mixed aerobic-anaerobic profile.

Anaerobic bacteria, which are major components of the normal human flora, can cause severe infections when mucosal barriers are disrupted [1.2.3, 1.7.1]. Understanding **what antibiotics are best for anaerobic coverage** is crucial, as these infections are often polymicrobial and require specific treatment strategies [1.7.1, 1.8.2].