Tag: Baroreflex

As one of the most widely used intravenous anesthetic agents, propofol is known to frequently cause dose-dependent hypotension, with incidence as high as 42% in some cohorts. Understanding the specific pathways explaining **how does propofol drop BP** is critical for safe administration in clinical settings, involving a complex interplay of systemic and cardiac effects.

Clinical case reports and studies have documented that the administration of vasopressin can lead to a significant decrease in heart rate, or bradycardia. This physiological response is not as simple as it seems, involving a complex interaction between the drug’s peripheral vasoconstrictive properties, its effects on the central nervous system, and reflex cardiovascular control.