Tag: Benadryl alternatives

While Benadryl is a common over-the-counter remedy for itching, many people experience unwanted drowsiness and other side effects. Fortunately, several effective alternatives exist for those seeking relief from allergic reactions, bug bites, and other skin irritations, so you have options for **what can I take instead of Benadryl for itching**.

A 2025 review in the journal *Healthcare* highlighted significant concerns regarding the chronic use of first-generation antihistamines like diphenhydramine (Benadryl), citing associations with cognitive impairment, particularly in older adults. For those seeking relief from allergies or occasional insomnia, finding a safer alternative to Benadryl has become a primary concern for many individuals and healthcare providers.