Tag: Bextra

Contrary to a widely-held belief, Celebrex (celecoxib) was *not* taken off the market; rather, its counterparts Vioxx and Bextra were. The question, **Why did Celebrex get taken off the market?**, stems from a widespread safety controversy involving the entire class of COX-2 inhibitor drugs in the early 2000s.

From 2013 to 2018, nearly 8,000 medications were recalled by pharmaceutical companies [1.8.5]. Several of these have been prominent painkillers. So, what pain medication was removed from the market, and for what reasons? This reveals much about post-market drug safety.

An estimated 30 million people use nonsteroidal anti-inflammatory drugs (NSAIDs) every day worldwide [1.11.1]. While generally effective, some have been taken off the market. This article explores which NSAIDs are banned and the reasons for their withdrawal.

In 2004, Merck's voluntary withdrawal of Vioxx, a popular pain reliever, impacted an estimated 20 million Americans who had taken the drug [1.9.2]. The central question became, **what NSAID was taken off the market** and for what reasons? This event triggered a major re-evaluation of drug safety.

On April 7, 2005, the U.S. Food and Drug Administration (FDA) requested that Pfizer voluntarily withdraw the painkiller Bextra from the market. The decision to pull Bextra off the market was based on an unfavorable risk-to-benefit profile, driven by evidence of serious cardiovascular side effects and life-threatening skin reactions.

Between 1953 and 2013, 462 medicinal products were withdrawn from the market due to adverse reactions [1.7.1]. When wondering, 'What pain pill did they take off the market?', several prominent examples come to mind, including propoxyphene (Darvocet) and rofecoxib (Vioxx) [1.2.2, 1.2.1].

In 2004, Bextra was a prominent pain medication, but can you still get Bextra today? The answer is no; the FDA requested its withdrawal in 2005 due to an increased risk of serious cardiovascular events and severe skin reactions [1.3.1, 1.3.2].