Tag: Bioidentical hormones

The use of menopausal Hormone Replacement Therapy (HRT) significantly declined after the 2002 Women's Health Initiative study raised initial safety concerns, but current understanding allows for greater personalization to minimize risks. Navigating these options to determine what is the safest hormone replacement therapy for an individual requires careful consideration with a healthcare provider.

Millions of people worldwide undergo hormone replacement therapy, but the question remains, **What is the safest hormone to take?** The answer is complex and highly dependent on individual health, lifestyle, and specific hormonal needs, requiring personalized medical consultation.

In 2023, progesterone was the 117th most commonly prescribed medication in the United States, with over 5 million prescriptions [1.2.5]. When considering supplementation, the crucial question becomes: **which form of progesterone is best** for your specific health needs?

While many people use the terms interchangeably, progestin is the key another name for progesterone, but it refers specifically to the synthetic version of the hormone. It is crucial for patients considering hormone therapies to understand the distinction, as bioidentical progesterone and synthetic progestins have different chemical structures and effects on the body.

From 1999 to 2020, the use of menopausal hormone therapy among postmenopausal women in the U.S. fell from approximately 27% to 5% [1.8.2]. For those considering it, asking 'Which is the best progesterone?' is a crucial first step toward personalized treatment.

Bioidentical progesterone is chemically and structurally identical to the hormone produced naturally by the body. For women seeking hormone replacement therapy, it is crucial to understand that both FDA-approved brands and custom-compounded formulations exist, each with significant differences in regulation and oversight.

While many people report gaining weight while taking progesterone, clinical research on a direct causal link is inconsistent [1.2.1]. Any weight change that does occur may be due to temporary water retention rather than an increase in fat mass [1.4.1]. This article explores the nuanced relationship between progesterone and weight.

Progesterone is a hormone naturally produced by the human body, but its medical versions are more complex, encompassing both natural and synthetic forms. This complexity leads to a common question: Is progesterone natural or synthetic?

Bioidentical hormones, including oral progesterone, are manufactured in a laboratory but are structurally identical to the hormones produced by the human body. When people ask, "Is there a natural progesterone pill?", they are often referring to this prescription-only oral micronized progesterone, which is not found in over-the-counter supplements.

An estimated 30% of women experience moderate to severe premenstrual syndrome (PMS), with many symptoms linked to hormone fluctuations [1.6.4]. The question then arises: **will taking progesterone help my mood?** For many, it can offer significant benefits, but the answer is complex.