What Does Amitriptyline Do to Your Bowels? Understanding the Gastrointestinal Effects
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4 min read
As a tricyclic antidepressant (TCA), amitriptyline primarily functions as an anticholinergic agent, which frequently results in constipation as a notable side effect. However, this very property—the slowing of bowel motility—is intentionally leveraged in low doses to treat specific gastrointestinal conditions like diarrhea-predominant Irritable Bowel Syndrome (IBS-D).
