What is the 10 8 6 rule for propofol?
•
4 min read
Originally derived from pharmacokinetic simulations in the late 1980s, the **10 8 6 rule for propofol** is a manual infusion regimen designed to help achieve and maintain a stable blood concentration during general anesthesia. This technique, also known as the Roberts or Bristol regimen, provides a foundational understanding of propofol's redistribution in the body, although it has largely been supplemented by modern computer-controlled methods.
