Tag: Buccal absorption

In recent years, personalized medicine has led to a shift in how medications are delivered, moving beyond traditional pills [1.7.5]. For those asking, 'What is the difference between a troche and a gummy?', the answer lies in their fundamental mechanism of drug absorption.

Originally derived from ancient Egyptian methods of creating medicated lozenges, a trokey (also known as a troche) is a modern pharmaceutical dosage form that dissolves slowly in the mouth to deliver medication. This unique method of drug administration offers significant benefits by allowing the active ingredients to be absorbed directly into the bloodstream through the oral mucosa, bypassing the liver's first-pass metabolism.

While the total nicotine content in a Zyn pouch is printed on the label, studies show that only a fraction of this amount is absorbed into the bloodstream. Understanding how much nicotine is absorbed from a Zyn is critical, as the delivery speed and amount differ significantly from traditional tobacco products like cigarettes.