Unraveling the Mechanism: Why do aminoglycosides cause neuromuscular blockade?
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4 min read
While uncommon, the administration of aminoglycoside antibiotics can lead to profound muscle weakness and respiratory depression in susceptible individuals, prompting the critical question: **Why do aminoglycosides cause neuromuscular blockade?**. This serious adverse effect is a result of the drug's direct interference with the signaling cascade at the body's neuromuscular junctions.
