The Decline of a Landmark Heart Medication: Why is Digoxin Not Used Anymore?
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4 min read
Derived from the foxglove plant, digoxin has been used for heart conditions for centuries [1.6.1]. However, its use has significantly declined. So, why is digoxin not used anymore as a first-line therapy? The primary reasons are its narrow therapeutic index, risk of toxicity, and the emergence of superior, safer medications [1.2.2].