Tag: Cardiovascular events

The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) in the early 2000s dramatically reshaped hypertension guidelines after finding that alpha-blockers like doxazosin performed worse than diuretics. This pivotal study is the primary reason why are alpha blockers not first line for hypertension today.

Ketorolac, a potent nonsteroidal anti-inflammatory drug (NSAID), carries multiple serious, potentially fatal side effect risks that have led to a boxed warning from the FDA. While it is a powerful analgesic, understanding what is the most concerning side effect of ketorolac is crucial for safe use, as risks significantly increase with higher doses and longer duration of treatment.

According to the FDA, certain birth control pills containing drospirenone, including Yaz, may be associated with a higher risk for blood clots than other progestin-containing pills. This serious potential health risk is the reason behind **what is the black box warning on Yaz birth control**.

Clinical trials like PEGASUS-TIMI 54 have demonstrated that the long term use of ticagrelor can significantly reduce the rate of major adverse cardiovascular events in high-risk patients with a prior heart attack. This approach is an extension of the initial standard dual antiplatelet therapy (DAPT) protocol, which typically lasts for a certain period following an acute coronary syndrome (ACS).

According to the World Health Organization, an estimated 1.28 billion adults aged 30–79 years worldwide have hypertension. Teldawn CH is a prescription medication used to treat this condition by combining two active ingredients that work synergistically to lower high blood pressure.