Tag: Cdk4 6 inhibitors

According to scientific reports, while letrozole itself is not typically the cause of kidney damage, a rise in creatinine levels can occur, particularly when it's part of a combination therapy with other cancer drugs. The question, 'Does letrozole affect creatinine levels?', therefore requires a comprehensive understanding of the drug's interactions.

In a 2011 study published in *The Lancet Oncology*, letrozole demonstrated superior efficacy to tamoxifen in preventing breast cancer recurrence, highlighting its status as a potent hormonal therapy. However, in specific situations, including advanced disease or the development of treatment resistance, a patient's medical team may explore therapies that offer greater potency or a different mechanism of action, addressing the question: **what is stronger than letrozole**?.