Tag: Cell membrane disruption

Before being largely replaced by safer alternatives, hexachlorophene was a widely used antimicrobial agent, known for its effectiveness against Gram-positive bacteria. Understanding what is the mechanism of action of hexachlorophene reveals how this bisphenol compound compromises bacterial viability through a dual approach involving membrane damage and metabolic interference.

In clinical trials, a single 1200 mg dose of Oritavancin was proven to be as effective as a 7–10 day course of vancomycin for certain acute bacterial skin and skin structure infections (ABSSSIs). This powerful, single-infusion treatment is possible because of a unique, multi-pronged mechanism of action that explains: How does Oritavancin work?