Is paracetamol a COX-1 inhibitor? Understanding its unique mechanism
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4 min read
Unlike traditional nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin, paracetamol (acetaminophen) does not cause significant gastrointestinal distress or affect blood clotting, leading to persistent questions about its mode of action. Because of its distinct profile, a key topic of inquiry is whether **is paracetamol a COX-1 inhibitor**, and the answer reveals a complex and primarily central mechanism.
