Tag: Chemical structure

The sulfonamide functional group, also known as sulphonamide, was first discovered in Germany in 1932 and became the basis for the first synthetic antibacterial drugs. So, what is the structure of sulphonamide? It is an organosulfur group, R-SO₂-NR'R'', that is a crucial component in many important medications.

Aminoglycoside antibiotics are a class of antimicrobial drugs characterized by their potent, bactericidal activity, first discovered in the 1940s. Their unique chemical structure, featuring amino sugars linked to an aminocyclitol ring, forms the basis for their mechanism of action against susceptible bacteria.

First isolated in 1952 from the bacterium *Saccharopolyspora erythraea*, erythromycin's chemical architecture is pivotal to its function as a macrolide antibiotic. The intricate structure, consisting of a macrocyclic lactone ring and two sugar units, defines its mechanism of action and serves as a blueprint for newer, more stable derivatives.

Cefixime is a semi-synthetic third-generation cephalosporin antibiotic, with research highlighting its potent efficacy against a broad spectrum of bacterial infections. Its powerful antibacterial action is directly linked to its complex chemical structure, which features a specific cephem core and strategically placed side chains.