Tag: Chemonucleolysis

One study found that patients with lower back symptoms treated with Discogel showed long-term durability of pain relief, with improvements continuing for at least 12 months. This minimally invasive treatment offers a potential long-lasting solution for those suffering from disc-related pain, but its exact longevity depends on several individual and clinical factors.

Anaphylaxis, a severe allergic reaction, occurred in up to 1% of patients treated with chymopapain, contributing to a complex debate about its safety. This article explores the full story of why was chymopapain discontinued despite its effectiveness for many.

First isolated in 1941 from the crude latex of the *Carica papaya* fruit, **what is chymopapain made of** is a natural proteolytic enzyme, historically known for its use in a procedure called chemonucleolysis.

An estimated 80% of people will experience back pain at some point, with some cases resulting from herniated discs. For a time, the drug chymopapain was used for a procedure called chemonucleolysis to address this issue, but its use was ultimately discontinued due to significant risks.