Tag: Chronic plaque psoriasis

According to the American Academy of Dermatology, many patients on methotrexate for psoriasis may start to see improvement in their symptoms within four to six weeks. This provides a starting point for understanding how quickly does methotrexate work on psoriasis, though maximum clearing often takes much longer.

In some long-term studies, methotrexate therapy has been shown to produce a 'good' effect in up to 76% of patients with extensive plaque psoriasis, while newer data suggests a wide range of responses depending on the patient and dosage. The ultimate success rate of methotrexate for psoriasis is influenced by several factors and is best understood through standardized metrics like the Psoriasis Area and Severity Index (PASI).