Tag: Citrulline

Oral L-citrulline supplementation is known to increase plasma arginine concentrations within 1 to 2 hours of ingestion. Understanding this pharmacokinetic profile is crucial for optimizing the timing and dosage of your supplement to address the common question: **how long does it take for citrulline to kick in**?

As an amino acid that converts into nitric oxide to relax blood vessels, citrulline can lower blood pressure and interact with certain medications. This makes it crucial to understand who should not take citrulline to prevent potentially dangerous health outcomes.