Tag: Citrulline malate

Approximately 20-30% of individuals may be 'non-responders' to creatine, meaning they experience minimal performance benefits from supplementation [1.9.3]. For these individuals and others seeking alternatives, several supplements offer comparable benefits. So, what is a good substitute for creatine?

Oral L-citrulline supplementation is known to increase plasma arginine concentrations within 1 to 2 hours of ingestion. Understanding this pharmacokinetic profile is crucial for optimizing the timing and dosage of your supplement to address the common question: **how long does it take for citrulline to kick in**?