Tag: Clinical decision making

Off-label drug use, prescribing a medication for a purpose not explicitly approved by regulators, accounts for a significant portion of prescriptions, highlighting the critical importance of understanding **what is the indication of drug administration**. An indication is the specific, evidence-based reason for using a drug, defined through a rigorous regulatory process to ensure safety and efficacy.

In medical education, a clinical pearl is a small, free-standing bit of clinically relevant information based on experience or observation [1.2.5, 1.2.8]. This article explains **what is a pearl in medicine**, its origins, and its significant role in fields like pharmacology.

For every hour of delayed treatment in sepsis, the risk of death increases by 4-9% [1.7.2]. This highlights the critical need for immediate action, which is the core principle behind **what is empiric dosing**: initiating treatment before a definitive diagnosis is confirmed [1.2.5, 1.3.1].

According to the World Health Organization, irrational prescribing is a leading cause of medication errors and adverse events worldwide. Following the golden rules of prescribing is therefore essential for healthcare professionals to maximize clinical effectiveness and patient safety. These principles provide a framework for making sound therapeutic decisions.