What is the definition of antibiotic failure? Answering a Complex Clinical Question
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5 min read
Antibiotic treatment failure, which is distinct from simple antibiotic resistance, is a major global health concern, with some studies on community-acquired pneumonia showing failure rates as high as 22%. The question, 'what is the definition of antibiotic failure?' touches upon a complex clinical scenario where antimicrobial therapy fails to cure an infection, leading to persistent or worsening patient outcomes.