What was the first FDA-approved kinase inhibitor?
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4 min read
In 2001, the U.S. Food and Drug Administration (FDA) approved imatinib (brand name Gleevec), marking a monumental shift in cancer treatment as it was the first rationally designed kinase inhibitor to directly target a specific cancer-causing protein. Its approval opened the door to a new era of precision medicine, demonstrating that targeted therapy could be a safe and highly effective alternative to conventional chemotherapy.