Tag: Cns disorders

First used as an anthelmintic agent in 1953, the cyclic compound known as piperazine and its many derivatives have a surprisingly wide range of applications in medicine. So, what are piperazines used for in modern pharmacology and beyond, and what accounts for their versatility?

According to scientific research, there is no recognized 'histamine M' receptor in the field of pharmacology. This query likely stems from a misunderstanding of the four distinct histamine receptors, designated as H1, H2, H3, and H4, which are involved in various physiological and pathological processes across the body.

The blood-brain barrier (BBB) prevents nearly 100% of large-molecule drugs from entering the brain, posing a massive challenge for treating neurological disorders [1.3.4]. This article explores what is the use of neuro spray, an innovative delivery method designed to bypass this barrier.

In September 2024, the FDA approved the first new class of antipsychotic medications in decades, containing the active muscarinic agonist **xanomeline**. This oral medication, marketed as Cobenfy, represents a significant paradigm shift by targeting cholinergic receptors to treat schizophrenia in adults.