Tag: Controlled release

Ocular inserts can increase the contact time of a medication on the eye's surface by up to 20 hours, significantly improving bioavailability compared to traditional eye drops. This advanced drug delivery system is classified primarily based on its solubility and drug release characteristics, offering various solutions for managing eye diseases.

Sustained-release (SR) formulations were first developed in the 1950s and 1960s to improve treatment effectiveness [1.2.3]. The primary question for many patients is, **what is the use of one SR capsules?** They are designed to release medication slowly, enhancing patient compliance and therapeutic outcomes [1.2.3, 1.2.4].

It's estimated that around 50% of patients with chronic illnesses do not take their medications as prescribed [1.5.2, 1.5.6]. Modified-release formulations like ER and SR help improve this by reducing dosing frequency. But **what is the difference between ER and sustained release?**

The global pharmaceutical drug delivery market was valued at approximately US$1.9 trillion in 2023 and is projected to grow, with oral delivery methods accounting for over 55% of the market share. Understanding **what are the different types of drug delivery** is crucial for appreciating advancements in modern medicine.

For many patients with ADHD, extended-release stimulant medications are formulated to provide symptom relief throughout the school or workday. A common dose is 20mg, and it is designed to work for a predictable duration, which offers a significant advantage over immediate-release formulations.

Seeing what looks like an intact pill in your stool is a surprisingly common experience, especially with certain controlled-release medications. This phenomenon, often called a "ghost pill," does not mean the drug wasn't absorbed, but understanding **what does a pooped out pill look like** can help alleviate concern.

Mucoadhesive drug delivery systems can extend the time a medication stays at its target site from just a few minutes to several hours, significantly boosting its effectiveness. Understanding the answer to 'how does mucoadhesive work?' is key to developing next-generation targeted therapies.

Polyacrylamide (PAM) hydrogels, a class of polymers known for their ability to absorb large quantities of water, are increasingly used in biomedical fields due to their soft, tissue-like consistency. In pharmacology, understanding what PAM hydrogel is involves recognizing its potential as a versatile platform for controlled drug delivery, tissue regeneration, and advanced wound care.

Did you know that matrix tablets were one of the earliest oral technologies used for extended-release drug delivery, with its foundational concepts established in the late 1950s? A matrix tablet is a sophisticated oral dosage form in which an active drug is uniformly dispersed within a rate-controlling polymer system to ensure its gradual release into the body over a predetermined period.

According to its product monograph, Foquest, a controlled-release methylphenidate for ADHD, has an onset of action within one hour due to its multi-layer bead technology. The medication is designed for a rapid initial release to kick in quickly, followed by sustained release throughout the day.