Does aspirin covalently inhibit COX? Unpacking the Irreversible Mechanism
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5 min read
A single low dose of aspirin can permanently inhibit platelet function for their entire lifespan of approximately 7-10 days. This remarkable effect stems from aspirin's unique ability to covalently inhibit COX enzymes, a mechanism that fundamentally sets it apart from other common non-steroidal anti-inflammatory drugs.
