What Pathway Does Ibuprofen Block? A Deep Dive into Its Mechanism
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4 min read
Over 17 million prescriptions for ibuprofen were filled in the United States in 2023 [1.9.3]. This popular NSAID provides relief by answering the question: **what pathway does ibuprofen block?** It non-selectively inhibits the cyclooxygenase (COX) pathway, reducing substances that cause pain and inflammation [1.2.5, 1.2.6].